S-Adenosyl-L-Homocysteine (50 mg)

S-Adenosyl-L-Homocysteine (50 mg) - Names and Identifiers

Name	5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
Synonyms	Adenosylhomocysteine Adenosyl-L-homocysteine S-Adenosyl-L-Homocysteine (50 mg) 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE L-5'-S-(3-AMino-3-carboxypropyl)- 5'-thioadenosine 5-S'-[(S)-3-Amino-3-carboxypropyl]-5'-thioadenosine 5μ-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5μ-Deoxyadenosine-5μ)-L-homocysteine (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methylsulfanyl]butanoic acid S-(5′-Adenosyl)-L-homocysteine,5′-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5′-Deoxyadenosine-5′)-L-homocysteine
CAS	979-92-0
EINECS	213-560-8
InChIKey	ZJUKTBDSGOFHSH-WFMPWKQPSA-N

S-Adenosyl-L-Homocysteine (50 mg) - Physico-chemical Properties

Molecular Formula	C14H20N6O5S
Molar Mass	384.41
Density	1.91±0.1 g/cm3(Predicted)
Melting Point	209-211 °C
Boling Point	787.5±70.0 °C(Predicted)
Solubility	Soluble in hot water, slightly soluble in cold water, ethanol, very slightly soluble in ether
Appearance	crystalline
Color	Off-White to Brown
BRN	99188
pKa	2.22±0.10(Predicted)
Storage Condition	-20°C
MDL	MFCD00037388
Physical and Chemical Properties	Bioactive S-Adenosyl-L-homocysteine (SAH, S-Adenosylhomocysteine, AdoHcy, Formycinylhomocysteine) is an (Methyltransferase Like 3-14) inhibitor of METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 value of 0.9 μM.

S-Adenosyl-L-Homocysteine (50 mg) - Risk and Safety

WGK Germany	3
FLUKA BRAND F CODES	8-10-23
HS Code	2934990002

S-Adenosyl-L-Homocysteine (50 mg) - Upstream Downstream Industry

Raw Materials	Adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-2',3'-O-(1-methylethylidene)-5'-thio- (9CI) DL-Homocysteine FORMIMINOGLYCINE NLUNILBRZXYZNX-KITWJDSFSA-N 5′-Chloro-5′-deoxy-2′,3′-O-isopropylideneadenosine L-HOMOCYSTEINE 5'-CHLORO-5'-DEOXYADENOSINE Adenosine Adenosine triphosphate
Downstream Products	5'-DEOXYADENOSINE

S-Adenosyl-L-Homocysteine (50 mg) - Reference

Reference

1. [IF=2.752] Yuting Zhang et al."Metabolomic Analysis and Identification of Sperm Freezability-Related Metabolites in Boar Seminal Plasma."Animals-Basel. 2021 Jul;11(7):1939

S-Adenosyl-L-Homocysteine (50 mg) - Introduction

5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE(5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE) is a compound with important biological activity. It is a structural analog of S-adenosyl-L-homocysteine in which the 5 '-oxygen atom in the glycoside group has been removed. It is a white crystalline powder with good solubility in water.

5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE plays a key regulatory role in cells. It is involved in a number of important biological processes, including DNA repair, gene expression, methylation and acetylation. In addition, it is also involved in antioxidant, anti-inflammatory and immune regulation and other physiological processes.

The preparation of 5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE is generally carried out by a chemical synthesis method. It can be synthesized from the reaction of adenosine and L-homocysteine.

Regarding safety, the toxicity of 5 '-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE is low. However, due to its regulatory effect in cells, the application of large doses may cause some adverse reactions. In the process of use, it is necessary to carry out appropriate dosage and treatment according to the specific situation. In addition, during storage and handling, it is necessary to avoid contact with oxygen to avoid oxidative deactivation.

Last Update：2024-04-09 21:54:55